Think of it as your 30 second elevator pitch Give an overview of where you are in your career what your experience brings to the table and why you are interviewing for the position
Keep it focused on the job and not personal until your asked something that leans to the more personal side. The cake = prior experience, icing why you’re a good fit and how you meet the requirements, sprinkles optional= sprinkle of personal
I would keep your responses relevant to the position you are interviewing for. If you have prior employment, include your notable accomplishments or professional affiliations (e.g. volunteer or community outreach). I would talk about QA projects that you have been involved and be prepared to talk about your processes. Other options would be to talk about your strengths,, or what you do to maintain your competencies, or or what you are looking for in an employer. Just make sure that if you are talking about multiple things that your conveying your ideas in a systematic manner.
Don't respond with answers you think they want to hear. Basically just be honest. Are you a mom? Single or married? What do you do on your off time? I feel they basically want to know if you'll stick around. If you have a family or you're trying to save to buy a home, etc. they know you will work and be dependable.